Shuai Wang Tri Lab

Research

You can find a selection and all our publications below.

Highlighted

AAV NRF2 Gene Therapy Preserves Retinal Structure and Function in Rodent Models of Oxidative Damage
AAV NRF2 Gene Therapy Preserves Retinal Structure and Function in Rodent Models of Oxidative Damage
Apolonia Gardner, Shuai Wang, Adam Daniels, Dan Li, Christine Wu, …, Genevieve Weist, Laura Barrio Real, Virginia Haurigot, Richard T. Born, Constance L. Cepko
openRxiv  ·  14 Jul 2025  ·  doi:10.1101/2025.07.09.663952

All

2025

AAV NRF2 Gene Therapy Preserves Retinal Structure and Function in Rodent Models of Oxidative Damage
AAV NRF2 Gene Therapy Preserves Retinal Structure and Function in Rodent Models of Oxidative Damage
Apolonia Gardner, Shuai Wang, Adam Daniels, Dan Li, Christine Wu, …, Genevieve Weist, Laura Barrio Real, Virginia Haurigot, Richard T. Born, Constance L. Cepko
openRxiv  ·  14 Jul 2025  ·  doi:10.1101/2025.07.09.663952
Development of a High-Speed Swept-Source OCT OCTA ORG System for Structural and Functional Imaging of the Living Mouse Retina
Development of a High-Speed Swept-Source OCT/OCTA/ORG System for Structural and Functional Imaging of the Living Mouse Retina
Yuxiang Zhou, Mingliang Zhou, Bo Wang, Xiaoting Yin, Jing Bai, Shuai Wang, Kai Neuhaus, Bernhard Baumann, Yifan Jian, Pengfei Zhang
IEEE Transactions on Instrumentation and Measurement  ·  01 Jan 2025  ·  doi:10.1109/TIM.2025.3606015

2024

Incidence Rate of Secondary Glaucoma Following Congenital Cataract Surgery: An In-Depth Systematic Review and Meta-Analysis
Incidence Rate of Secondary Glaucoma Following Congenital Cataract Surgery: An In-Depth Systematic Review and Meta-Analysis
Li Li, Xi Wang, Changyang Liu, Shuai Wang, Xiaochen Wang
American Journal of Ophthalmology  ·  01 Sep 2024  ·  doi:10.1016/j.ajo.2024.04.021
Fucoidan modulates SIRT1 and NLRP3 to alleviate hypertensive retinopathy: in vivo and in vitro insights
Fucoidan modulates SIRT1 and NLRP3 to alleviate hypertensive retinopathy: in vivo and in vitro insights
Jing Li, Xiaochen Wang, Jie Bai, Huangzhao Wei, Wenbo Wang, Shuai Wang
Journal of Translational Medicine  ·  15 Feb 2024  ·  doi:10.1186/s12967-024-04877-6
CD11b mediates hypertensive cardiac remodeling by regulating macrophage infiltration and polarization
CD11b mediates hypertensive cardiac remodeling by regulating macrophage infiltration and polarization
Yun-Long Zhang, Jie Bai, Wei-Jia Yu, Qiu-Yue Lin, Hui-Hua Li
Journal of Advanced Research  ·  01 Jan 2024  ·  doi:10.1016/j.jare.2023.02.010

2023

Fucoidan inhibits apoptosis and improves cardiac remodeling by inhibiting p53 transcriptional activation through USP22 Sirt 1
Fucoidan inhibits apoptosis and improves cardiac remodeling by inhibiting p53 transcriptional activation through USP22/Sirt 1
Shuai Wang, Jie Bai, Yilin Che, Weikun Qu, Jing Li
Frontiers in Pharmacology  ·  30 May 2023  ·  doi:10.3389/fphar.2023.1164333
Integrin CD11b Contributes to Hypertension and Vascular Dysfunction Through Mediating Macrophage Adhesion and Migration
Integrin CD11b Contributes to Hypertension and Vascular Dysfunction Through Mediating Macrophage Adhesion and Migration
Qiu-Yue Lin, Jie Bai, Yun-Long Zhang, Hui-Hua Li
Hypertension  ·  01 Jan 2023  ·  doi:10.1161/HYPERTENSIONAHA.122.20328

2022

Highly Biocompatible Apigenin-Loaded Silk Fibroin Nanospheres: Preparation, Characterization, and Anti-Breast-Cancer Activity
Highly Biocompatible Apigenin-Loaded Silk Fibroin Nanospheres: Preparation, Characterization, and Anti-Breast-Cancer Activity
Weikun Qu, Peng Ji, Xibin Han, Xianglong Wang, Yang Li, Jin Liu
Polymers  ·  21 Dec 2022  ·  doi:10.3390/polym15010023
CXCL1-CXCR2 signalling mediates hypertensive retinopathy by inducing macrophage infiltration
CXCL1-CXCR2 signalling mediates hypertensive retinopathy by inducing macrophage infiltration
Shuai Wang, Jie Bai, Yun-Long Zhang, Qiu-Yue Lin, Xiao Han, Wei-Kun Qu, Peng-Fei Zhang, Yu-Song Ge, Qi Zhao, Hui-Hua Li
Redox Biology  ·  01 Oct 2022  ·  doi:10.1016/j.redox.2022.102438

2021

Systematic analysis of the expression and prognosis relevance of FBXO family reveals the significance of FBXO1 in human breast cancer
Systematic analysis of the expression and prognosis relevance of FBXO family reveals the significance of FBXO1 in human breast cancer
Yaqian Liu, Bo Pan, Weikun Qu, Yilong Cao, Jun Li, Haidong Zhao
Cancer Cell International  ·  23 Feb 2021  ·  doi:10.1186/s12935-021-01833-y
Intravitreal conbercept improves outcome of proliferative diabetic retinopathy through inhibiting inflammation and oxidative stress
Intravitreal conbercept improves outcome of proliferative diabetic retinopathy through inhibiting inflammation and oxidative stress
Jian-Ping Xia, Sheng-Qiang Liu, Shuai Wang
Life Sciences  ·  01 Jan 2021  ·  doi:10.1016/j.lfs.2020.118795

2020

Immunosubunit β5i Knockout Suppresses Neovascularization and Restores Autophagy in Retinal Neovascularization by Targeting ATG5 for Degradation
Immunosubunit β5i Knockout Suppresses Neovascularization and Restores Autophagy in Retinal Neovascularization by Targeting ATG5 for Degradation
Liyang Ji, Li Li, Ying Zhao, Shengqiang Liu, Jingmin Li, Jinsong Zhang, Qi Zhao, Shuai Wang
Investigative Opthalmology & Visual Science  ·  28 Dec 2020  ·  doi:10.1167/iovs.61.14.30
Ablation of Immunoproteasome β5i Subunit Suppresses Hypertensive Retinopathy by Blocking ATRAP Degradation in Mice
Ablation of Immunoproteasome β5i Subunit Suppresses Hypertensive Retinopathy by Blocking ATRAP Degradation in Mice
Shuai Wang, Jing Li, Tong Wang, Jie Bai, Yun-Long Zhang, Qiu-Yue Lin, Jing-min Li, Qi Zhao, Shu-Bin Guo, Hui-Hua Li
Molecular Therapy  ·  01 Jan 2020  ·  doi:10.1016/j.ymthe.2019.09.025

2019

Immunoproteasome Subunit β5i Promotes Ang II Angiotensin II Induced Atrial Fibrillation by Targeting ATRAP Ang II Type I Receptor Associated Protein Degradation in Mice
Immunoproteasome Subunit β5i Promotes Ang II (Angiotensin II)–Induced Atrial Fibrillation by Targeting ATRAP (Ang II Type I Receptor–Associated Protein) Degradation in Mice
Jing Li, Shuai Wang, Yun-Long Zhang, Jie Bai, Qiu-Yue Lin, Rui-Sheng Liu, Xiao-Hong Yu, Hui-Hua Li
Hypertension  ·  01 Jan 2019  ·  doi:10.1161/HYPERTENSIONAHA.118.11813
Taurine rescues the arsenic-induced injury in the pancreas of rat offsprings and in the INS-1 cells
Taurine rescues the arsenic-induced injury in the pancreas of rat offsprings and in the INS-1 cells
Qiaoting Zhang, Jie Bai, Xiaofeng Yao, Liping Jiang, Wei Wu, …, Ni Gao, Tianming Qiu, Guang Yang, Tesfaldet Habtemariam Hidru, Xiance Sun
Biomedicine & Pharmacotherapy  ·  01 Jan 2019  ·  doi:10.1016/j.biopha.2018.10.134

2018

The immunoproteasome subunit LMP10 mediates angiotensin II-induced retinopathy in mice
The immunoproteasome subunit LMP10 mediates angiotensin II-induced retinopathy in mice
Shuai Wang, Jing Li, Jie Bai, Jing-Min Li, Yi-Lin Che, Qiu-Yue Lin, Yun-Long Zhang, Hui-Hua Li
Redox Biology  ·  01 Jun 2018  ·  doi:10.1016/j.redox.2018.02.022
Novel Role for the Immunoproteasome Subunit PSMB10 in Angiotensin II Induced Atrial Fibrillation in Mice
Novel Role for the Immunoproteasome Subunit PSMB10 in Angiotensin II–Induced Atrial Fibrillation in Mice
Jing Li, Shuai Wang, Jie Bai, Xiao-Lei Yang, Yun-Long Zhang, Yi-Lin Che, Hui-Hua Li, Yan-Zong Yang
Hypertension  ·  01 May 2018  ·  doi:10.1161/HYPERTENSIONAHA.117.10390